Machines are usually more precise and efficient than humans when carrying out repeatable tasks. Thus, replacing or aiding work processes susceptible to human errors, quality defects and safety issues with machines will have an impact on quality and redundant waste. The application of AI in robotics and the same robotics extends the opportunity for automation of manual task increasing the sustainability, safety & security of the production and its green transition, reducing the environmental impact -efficient reduction of the waste and optimizing product quality toward zero defect, process, and manpower- and achieve a more safe and secure working area to easier the human- machine, machine - machine co working.There are many kinds of autonomous systems, robots and working machines. Just to give an insight into their widespread adoption, can be categorised by purpose, as follows:Industrial machines and robots:Manufacturing (e.g. welding, assembling, spray gun robots).Material handling (e.g. conveyors, warehouse robots, trucks).Consumer robots:Domestic (e.g. robotic lawn mowers or vacuum cleaners).Care (e.g. lifting or carrying robots).Healthcare and medical robots:Robotic surgery, hospital ward automation.Medical tests and hospital care, remote healthcare.Medical imaging, exoskeletons.Moving machines:Mining machines (e.g. drilling machines, dumpers, conveyors).Forestry (e.g. forest harvester), agriculture (e.g. tractors, appliances).Construction (e.g. excavators, road graders, building robots).Logistics and sorting centres (e.g. cranes, straddle carriers, reachers, conveyor belts, sorting machines, trucks).Military robots and machines.Transport:Vehicles, trucks and cars, trains, trams, buses, subways.Aviation (e.g. aeroplanes, helicopters, unmanned aerial vehicles, UAVs).Marine (e.g. vessels, ships, auto-piloted ships), submarine (e.g. auto-piloted submarines).Utilities and critical infrastructures:Extraction (e.g. drills for gas, oil).Surveillance (e.g. quadcopters, drones).Safety, security (e.g. infrared sensors, fire alarms, border guards).Energy power plants sensors and actuators (e,g, production and distribution).Transportation (e.g. moving bridges, rail exchanges).The main aims and evolution trends of robots and autonomous systems in digital industry are oriented toward:Production efficiency, speed and reduced costs,Higher precision and quality,Safety in working conditions,To scale up “smart and high-end manufacturing”.As is evident from the above, robots and machines and in particular autonomous systems are involved in all application Chapters of this SRIA in addition to Digital Industry – i.e. Digital Society, Health and Wellbeing, Mobility, Energy,and Agrifood and Natural Resources- and are positively impacted by any improvement on both technological layers of the SRIA, foundational and cross-sectional technology.There is undoubtedly a move to increase the level of automation and degree of digitalisation in industry, which will ultimately lead to fully autonomous systems.However, between low and high technology manufacturing two extremes, entirely manual and fully autonomous, there will always lie a large area of semi-autonomous equipment, units, machines, vehicles, lines, factories and sites that are worth keeping somewhat below 100% autonomous or digitised. The reasons for this include:a fully autonomous solution may simply be (technically) near to impossible to design, implement and test.if achievable, they may be too expensive to be realised.a fully autonomous solution may be too complex, brittle, unstable, unsafe, etc.a less-demanding semi-automatic solution may be easier to realise to a fully satisfactory level.When the extent of automation and digitalisation are gradually, reasonably and professionally increased, often step by step, they may bring proportionally significant competitive advantages and savings that strengthen the position of digital industries overall. However, since the extent of automation and digitalisation remains well below 100%, any potential negative effects to employment are still either negligible or non-existent. On the contrary, the competitive advantages due to the adoption of robotics and autonomous system solutions increases market company position and, generally, enhances the need for more people in the respective businesses.Key focus areasAutonomous functions of systems:Advances in Artificial intelligent made easier to achieve fully autonomous systems solutions, exploiting the automation of knowledge and service work into operative physical layer on different application domains, in which to automate work tasks increasingly reducing the need for human intervention and, at the same time, allowing to highlight additional innovative functions, such as in the automotive in which more autonomous vehicles are expected to play a key role in the future of urban transportation systems. Such a challenge in a so complex scenario will promote significant advances in any autonomous functions of the many systems which are integral part of the Digital Industry ecosystem.Autonomous robots are key enabling systems towards implementation of autonomous functions shopfloors. Immediate benefits will be additional safety, increased productivity, greater accessibility, better efficiency, and positive impact on the environment. Here follows a modified picture from giving a generalized view of autonomous systems technologies and functionalities focused on autonomous vehicles, but with a rich affinity with any sort of autonomous system required building blocks.Diagram Description automatically generatedFigure 7 A generalised overview of autonomous system (AS) technologies and functionalities. Adapted from Pendleton, S.D., Andersen, A., Du, X., Shen, X., Meghjani, M., Eng, Y.H., Rus, D., Ang, M.H.Jr. (2017). “Perception, Planning, Control, and Coordination for Autonomous Vehicles. Machines”, 2017.The following picture shows matching of ISA95 standard that define control functions and other enterprise functions with building blocks of autonomous systems. The autonomy is expected to increase in the level 2 and Level 3 of ANSI/ISA95.C:\Users\bianchial\Pictures\The-conventional-automation-pyramid-according-to-the-ANSI-ISA-9.pngFigure 8: ISA95 Hierarchy Model with building blocks of Autonomous Systems according to the 5 levels of the conventional automation pyramidSafety and security in autonomous systems:Current standards of safety requirements for autonomous machines categorise safety into four approaches.On-board sensors and safety systems for machines that work among humans and other machines but is restricted to indoor applications.An isolated autonomous machine that works in a separated working area, mostly an intensive outdoor environment where other machines or humans are monitored.Machine perception and forecast of expected and/or unexpected human activities aimed at: (i) assisting human activities and movements with a proactive behaviour; (ii) preserving human health and safety; and (iii) preserving the integrity of machinery.An operator is responsible for reacting to a hazardous situation encountered by the autonomous machine when being provided with enough time between alert and transferring responsibility.Requirements management and conceptual modelling of autonomous systems:With the increasing complexity of autonomous functionality in both AV and ADAS systems, traditional methodologies of developing safety critical software are becoming inadequate, and not only for autonomous driving, but in any industrial field of application of autonomous systems. Since autonomous systems are designed to operate in complicated real-world domains, they will be expected to handle and react appropriately a near endless variety of possible scenarios, meeting expectations from various stakeholders such as the internal engineering teams, people involved in the autonomous systems managements (e.g. passengers, drivers, workers, e-Health patients), regulatory authorities, and commercial autonomous vehicles/robots fleet operators.Human–machine interaction in autonomous systems:Improvements on sensing capabilities, on actuation control, IIoT and SoS distributed capability are, in robotics and autonomous systems, the key enabler for:Human–robot interaction or human–machine cooperation.Transparency of operations between human and advanced machine systems (AMS) in uncertain conditions.Remote operation and advanced perception, AS oversight and tactical awareness.Autonomy intended to enhance human capabilities.Natural human interaction with autonomous systems.Assisted, safety-oriented and proactive robot interaction with humansDigital design practices including digital verification and validation (V&V):Automatic or semi-automatic V&VA digital design environment, digital twins, physical mock-ups.Sub-task automation development, generation of training data and testing solutions and field data augmentation, according to a handful of global machine manufacturers.Machine state estimation (assigning a value to an unknown system state variable based on measurements from that system).Simulators and autonomous systems:Process model based and product 3D models approaches , environment and object models and simulation tools.Early design phase simulators.Robotic test environments.Empirical or semi-empirical simulators, making use of both real and simulated data collected from previous experiments.Off-road environments.Autonomous capabilities development in a digital environmentAutonomous decision takingSelf-evolving capabilities.Exploitation of knowledge in cognitive flexibility and in adaptability of the reaction